Step-by-Step Lesson • Step 1 of 6

ARCH-B-10: Renal Vessels, Nephron Ultrafiltration, Selective PCT Reabsorption & ADH Osmoregulation

Full 15-Q Timed Drill
Step 1 of 6 • The Core Idea

ARCH-B-10: Why the 135s Classroom Method Fails Under the 90s Clock

Standard Classroom Method (Too Slow)~135s (Blows 90s Clock)
Trace each solute through the nephron:
- Plasma proteins: Mr>68,000M_r > 68{,}000; blocked by the glomerular basement membrane   ⟹  (−)\implies (-) in filtrate and (−)(-) in urine.
- Glucose: small molecule (Mr=180M_r = 180); filtered freely into Bowman's capsule (+)(+), then **100%100\% selectively reabsorbed in the PCT**   ⟹  (−)\implies (-) in final urine.
- Urea: small molecule; filtered freely (+)(+) and concentrated as water is reabsorbed   ⟹  (+)\implies (+) in final urine.
The Fast ShortcutTarget: 35s (Saves 100s)
Bowman's capsule has **glucose (++) & urea (++), no protein (−-)**; PCT reabsorbs 100%100\% of glucose   ⟹  \implies Urine has **only urea (++)**.
Where Students Lose Time: In 5 past UAT-UK questions (2.15% of Biology), candidates lose 100s by proteins and blood cells are too large for ultrafiltration; glucose is filtered and then completely reabsorbed in the proximal convoluted tubule. Instead, apply B9 with Maths 1 skill M4.14.
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