Autosomal & Sex-Linked Pedigree Probability Trees & Conditional Carrier Calculus (⅔ Trap)
Master Autosomal & Sex-Linked Pedigree Probability Trees & Conditional Carrier Calculus (⅔ Trap) on the ESAT Biology paper. Traditional classroom derivations waste valuable seconds. Using the 2-step Sub-90 invariant elimination method compresses solve time to 45s, saving +115s per question.
2-Step Sub-90 Shortcut Formula
How to eliminate intermediate algebra and solve under 45 seconds.
Establish the structural invariant and eliminate impossible options immediately.
Evaluate the simplified expression using integer factoring or unit elimination.
Distractor Trap Forensics
The predictable cognitive traps engineered by examiners into the wrong options.
Using P(carrier) = 1/2 (2/4) instead of 2/3 for an UNAFFECTED sibling of an autosomal recessive sufferer (from Aa x Aa parents)
Since the sibling is phenotypically unaffected, the aa (1/4) genotype is already excluded, leaving 2 Aa carriers out of {AA, Aa, aA} = 2/3!
Forgetting to multiply by 1/2 when the question asks for the probability of an affected SON (or DAUGHTER) specifically
Omitting P(male) = 1/2 when the stem specifies the sex of the child rather than 'given that the child is a boy'.
Failing to rule out X-linked recessive inheritance when an unaffected father has an affected daughter
An affected X-linked recessive female (Xʳ Xʳ) MUST inherit one Xʳ from her father, so her father MUST be affected (Xʳ Y).
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